Cancer_code |
Cancer_name |
Total Number of All Mutations |
Total Number of Nonsynonymous Mutations |
Average Nonsynonymous Mutations per Sample |
Number of Samples |
Number of Genes |
Top Mutated Genes Ranked by Number of Samples affected) |
THCA |
Thyroid carcinoma |
7448 |
5687 |
11 |
509 |
4999 |
BRAF(242)|NRAS(34)|TTN(15)|HRAS(14)|TG(11) |
LAML |
Acute Myeloid Leukemia |
2514 |
2039 |
12 |
173 |
1834 |
FLT3(57)|NPM1(54)|DNMT3A(51)|IDH2(20)|IDH1(19) |
LGG |
Brain Lower Grade Glioma |
9879 |
7583 |
14 |
530 |
5956 |
IDH1(221)|TP53(146)|ATRX(118)|CIC(56)|NOTCH1(31) |
OV |
Ovarian serous cystadenocarcinoma |
20091 |
15866 |
52 |
307 |
9931 |
TP53(276)|TTN(61)|USH2A(20)|FAT3(19)|CSMD3(18) |
PRAD |
Prostate adenocarcinoma |
39736 |
30335 |
61 |
498 |
13180 |
FRG1BP(97)|TTN(64)|TP53(61)|TUBB8P7(60)|DNM1P47(60) |
BRCA |
Breast invasive carcinoma |
89158 |
70484 |
64 |
1100 |
17281 |
PIK3CA(319)|TP53(301)|TTN(175)|CDH1(113)|GATA3(97) |
KIRC |
Kidney renal clear cell carcinoma |
42206 |
35177 |
66 |
534 |
13314 |
VHL(225)|PBRM1(139)|TTN(78)|MUC4(77)|MUC16(58) |
BLCA |
Bladder Urothelial Carcinoma |
39231 |
29409 |
72 |
408 |
13362 |
TTN(79)|TP53(64)|MUC16(43)|KMT2D(36)|ARID1A(34) |
LUSC |
Lung squamous cell carcinoma |
65239 |
49863 |
100 |
501 |
15031 |
TP53(145)|TTN(134)|CSMD3(81)|RYR2(77)|MUC16(77) |
GBM |
Glioblastoma multiforme |
21948 |
16766 |
101 |
166 |
9685 |
PTEN(90)|TP53(84)|EGFR(77)|TTN(77)|MUC16(47) |
LUAD |
Lung adenocarcinoma |
72187 |
56549 |
109 |
517 |
14994 |
TTN(114)|TP53(106)|MUC16(91)|RYR2(82)|CSMD3(81) |
LIHC |
Liver hepatocellular carcinoma |
53646 |
42009 |
113 |
373 |
14823 |
TP53(116)|TTN(109)|CTNNB1(97)|MUC16(54)|ALB(43) |
CESC |
Cervical squamous cell carcinoma and endocervical adenocarcinoma |
45302 |
35883 |
117 |
306 |
15428 |
TTN(69)|PIK3CA(53)|MUC4(37)|KMT2C(29)|MUC16(28) |
PAAD |
Pancreatic adenocarcinoma |
30341 |
22653 |
127 |
179 |
11608 |
KRAS(136)|TP53(104)|SMAD4(37)|TTN(35)|CDKN2A(22) |
COADREAD |
Colon and Rectum adenocarcinoma |
84426 |
65526 |
172 |
382 |
15894 |
APC(165)|TP53(120)|KRAS(97)|TTN(87)|SYNE1(49) |
HNSC |
Head and Neck squamous cell carcinoma |
119867 |
91733 |
176 |
522 |
17678 |
TP53(366)|TTN(227)|FAT1(115)|CDKN2A(113)|CSMD3(107) |
SKCM |
Skin Cutaneous Melanoma |
323328 |
218711 |
463 |
472 |
18861 |
TTN(278)|MUC16(250)|BRAF(189)|DNAH5(179)|PCLO(160) |
UCEC |
Uterine Corpus Endometrial Carcinoma |
183989 |
143471 |
811 |
177 |
18875 |
PTEN(161)|PIK3CA(132)|ARID1A(83)|PIK3R1(83)|TTN(80) |