SL Portal Data Summary

Gene Expression Data
Cancer_code Cancer_name Sample_Count_Total Gene_Count_Total Gene_Count_UP Gene_Count_Down
BLCA Bladder Urothelial Carcinoma 408 21889 1676(8%) 891(4%)
BRCA Breast invasive carcinoma 1100 21889 1606(7%) 778(4%)
CESC Cervical squamous cell carcinoma and endocervical adenocarcinoma 306 21889 3519(16%) 1517(7%)
COADREAD Colon and Rectum adenocarcinoma 382 21889 1434(7%) 1000(5%)
GBM Glioblastoma multiforme 166 21889 2151(10%) 1846(8%)
HNSC Head and Neck squamous cell carcinoma 522 21889 869(4%) 1202(5%)
KIRC Kidney renal clear cell carcinoma 534 21889 1808(8%) 806(4%)
LAML Acute Myeloid Leukemia 173 21889 2855(13%) 4882(22%)
LGG Brain Lower Grade Glioma 530 21889 1593(7%) 3625(17%)
LIHC Liver hepatocellular carcinoma 373 21889 1810(8%) 226(1%)
LUAD Lung adenocarcinoma 517 21889 2368(11%) 564(3%)
LUSC Lung squamous cell carcinoma 501 21889 2448(11%) 1282(6%)
OV Ovarian serous cystadenocarcinoma 307 21889 1170(5%) 2638(12%)
PAAD Pancreatic adenocarcinoma 179 20423 1417(7%) 1338(7%)
PRAD Prostate adenocarcinoma 498 21889 402(2%) 410(2%)
SKCM Skin Cutaneous Melanoma 472 21889 1019(5%) 3149(14%)
THCA Thyroid carcinoma 509 21889 879(4%) 230(1%)
UCEC Uterine Corpus Endometrial Carcinoma 177 21889 1851(8%) 1022(5%)


Gene Mutation Data
Cancer_code Cancer_name Total Number of All Mutations Total Number of Nonsynonymous Mutations Average Nonsynonymous Mutations per Sample Number of Samples Number of Genes Top Mutated Genes Ranked by Number of Samples affected)
BRCA Breast invasive carcinoma 89158 70484 64 1100 17281 PIK3CA(319)|TP53(301)|TTN(175)|CDH1(113)|GATA3(97)
KIRC Kidney renal clear cell carcinoma 42206 35177 66 534 13314 VHL(225)|PBRM1(139)|TTN(78)|MUC4(77)|MUC16(58)
LGG Brain Lower Grade Glioma 9879 7583 14 530 5956 IDH1(221)|TP53(146)|ATRX(118)|CIC(56)|NOTCH1(31)
HNSC Head and Neck squamous cell carcinoma 119867 91733 176 522 17678 TP53(366)|TTN(227)|FAT1(115)|CDKN2A(113)|CSMD3(107)
LUAD Lung adenocarcinoma 72187 56549 109 517 14994 TTN(114)|TP53(106)|MUC16(91)|RYR2(82)|CSMD3(81)
THCA Thyroid carcinoma 7448 5687 11 509 4999 BRAF(242)|NRAS(34)|TTN(15)|HRAS(14)|TG(11)
LUSC Lung squamous cell carcinoma 65239 49863 100 501 15031 TP53(145)|TTN(134)|CSMD3(81)|RYR2(77)|MUC16(77)
PRAD Prostate adenocarcinoma 39736 30335 61 498 13180 FRG1BP(97)|TTN(64)|TP53(61)|TUBB8P7(60)|DNM1P47(60)
SKCM Skin Cutaneous Melanoma 323328 218711 463 472 18861 TTN(278)|MUC16(250)|BRAF(189)|DNAH5(179)|PCLO(160)
BLCA Bladder Urothelial Carcinoma 39231 29409 72 408 13362 TTN(79)|TP53(64)|MUC16(43)|KMT2D(36)|ARID1A(34)
COADREAD Colon and Rectum adenocarcinoma 84426 65526 172 382 15894 APC(165)|TP53(120)|KRAS(97)|TTN(87)|SYNE1(49)
LIHC Liver hepatocellular carcinoma 53646 42009 113 373 14823 TP53(116)|TTN(109)|CTNNB1(97)|MUC16(54)|ALB(43)
OV Ovarian serous cystadenocarcinoma 20091 15866 52 307 9931 TP53(276)|TTN(61)|USH2A(20)|FAT3(19)|CSMD3(18)
CESC Cervical squamous cell carcinoma and endocervical adenocarcinoma 45302 35883 117 306 15428 TTN(69)|PIK3CA(53)|MUC4(37)|KMT2C(29)|MUC16(28)
PAAD Pancreatic adenocarcinoma 30341 22653 127 179 11608 KRAS(136)|TP53(104)|SMAD4(37)|TTN(35)|CDKN2A(22)
UCEC Uterine Corpus Endometrial Carcinoma 183989 143471 811 177 18875 PTEN(161)|PIK3CA(132)|ARID1A(83)|PIK3R1(83)|TTN(80)
LAML Acute Myeloid Leukemia 2514 2039 12 173 1834 FLT3(57)|NPM1(54)|DNMT3A(51)|IDH2(20)|IDH1(19)
GBM Glioblastoma multiforme 21948 16766 101 166 9685 PTEN(90)|TP53(84)|EGFR(77)|TTN(77)|MUC16(47)